2mkc: Difference between revisions
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==Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex== | ==Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex== | ||
<StructureSection load='2mkc' size='340' side='right' caption='[[2mkc | <StructureSection load='2mkc' size='340' side='right'caption='[[2mkc]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mkc]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MKC OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2mkc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MKC FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mkc OCA], [https://pdbe.org/2mkc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mkc RCSB], [https://www.ebi.ac.uk/pdbsum/2mkc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mkc ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/IST3_YEAST IST3_YEAST] Required for pre-mRNA splicing and spliceosome assembly. As part of the pre-mRNA retention and splicing (RES) complex, required for nuclear pre-mRNA retention and efficient splicing. Required for MER1-activated splicing.<ref>PMID:11287609</ref> <ref>PMID:15565172</ref> <ref>PMID:14973223</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2mkc" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Becker | [[Category: Large Structures]] | ||
[[Category: Luhrmann | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Munari | [[Category: Becker S]] | ||
[[Category: Schneider | [[Category: Luhrmann R]] | ||
[[Category: Trowitzsch | [[Category: Munari F]] | ||
[[Category: Wahl | [[Category: Schneider C]] | ||
[[Category: Wysoczanski | [[Category: Trowitzsch S]] | ||
[[Category: Xiang | [[Category: Wahl MC]] | ||
[[Category: Zweckstetter | [[Category: Wysoczanski P]] | ||
[[Category: Xiang S]] | |||
[[Category: Zweckstetter M]] | |||