1z72: Difference between revisions

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[[Image:1z72.gif|left|200px]]


{{Structure
==Structure of a putative transcriptional regulator from Streptococcus pneumoniae==
|PDB= 1z72 |SIZE=350|CAPTION= <scene name='initialview01'>1z72</scene>, resolution 1.45&Aring;
<StructureSection load='1z72' size='340' side='right'caption='[[1z72]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
<table><tr><td colspan='2'>[[1z72]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z72 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
|GENE= SP0716 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 Streptococcus pneumoniae TIGR4])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [https://pdbe.org/1z72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB], [https://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z72 ProSAT], [https://www.topsan.org/Proteins/MCSG/1z72 TOPSAN]</span></td></tr>
 
</table>
'''Structure of a putative transcriptional regulator from Streptococcus pneumoniae'''
== Function ==
 
[https://www.uniprot.org/uniprot/A0A0H2UP67_STRPN A0A0H2UP67_STRPN] Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).[PIRNR:PIRNR003170]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1Z72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA].
Check<jmol>
[[Category: Single protein]]
  <jmolCheckbox>
[[Category: Streptococcus pneumoniae tigr4]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z72_consurf.spt"</scriptWhenChecked>
[[Category: Abdullah, J.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Cuff, M E.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Joachimiak, A.]]
  </jmolCheckbox>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z72 ConSurf].
[[Category: Zhou, M.]]
<div style="clear:both"></div>
[[Category: ACY]]
__TOC__
[[Category: MG]]
</StructureSection>
[[Category: mcsg]]
[[Category: Large Structures]]
[[Category: midwest center for structural genomic]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: protein structure initiative]]
[[Category: Abdullah J]]
[[Category: psi]]
[[Category: Cuff ME]]
[[Category: streptococcus pneumoniae]]
[[Category: Joachimiak A]]
[[Category: structural genomic]]
[[Category: Zhou M]]
[[Category: transcription regulator]]
[[Category: transcriptional regulator]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:31:59 2008''

Latest revision as of 08:03, 17 October 2024

Structure of a putative transcriptional regulator from Streptococcus pneumoniaeStructure of a putative transcriptional regulator from Streptococcus pneumoniae

Structural highlights

1z72 is a 2 chain structure with sequence from Streptococcus pneumoniae TIGR4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.45Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

A0A0H2UP67_STRPN Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).[PIRNR:PIRNR003170]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1z72, resolution 1.45Å

Drag the structure with the mouse to rotate

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