1yxm: Difference between revisions

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-[[Image:1yxm.gif|left|200px]]
- {{Structure
+==Crystal structure of peroxisomal trans 2-enoyl CoA reductase==
-|PDB= 1yxm |SIZE=350|CAPTION= <scene name='initialview01'>1yxm</scene>, resolution 1.90&Aring;
+<StructureSection load='1yxm' size='340' side='right'caption='[[1yxm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=ADE:ADENINE'>ADE</scene>
+<table><tr><td colspan='2'>[[1yxm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YXM FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Acyl-CoA_dehydrogenase_(NADP(+)) Acyl-CoA dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.8 1.3.1.8]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-|GENE= pecr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yxm OCA], [https://pdbe.org/1yxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yxm RCSB], [https://www.ebi.ac.uk/pdbsum/1yxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yxm ProSAT]</span></td></tr>
+</table>
-'''Crystal structure of peroxisomal trans 2-enoyl CoA reductase'''
+== Function ==
+[https://www.uniprot.org/uniprot/PECR_HUMAN PECR_HUMAN] Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-YXM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXM OCA].
+Check<jmol>
-[[Category: Acyl-CoA dehydrogenase (NADP(+))]]
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/1yxm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yxm ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C.]]
+[[Category: Arrowsmith C]]
-[[Category: Delft, F Von.]]
+[[Category: Edwards AM]]
-[[Category: Edwards, A M.]]
+[[Category: Jansson A]]
-[[Category: Jansson, A.]]
+[[Category: Ng S]]
-[[Category: Ng, S.]]
+[[Category: Oppermann U]]
-[[Category: Oppermann, U.]]
+[[Category: Sharma S]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Sundstrom M]]
-[[Category: Sharma, S.]]
+[[Category: Von Delft F]]
-[[Category: Sundstrom, M.]]
-[[Category: ADE]]
-[[Category: PO4]]
-[[Category: SO4]]
-[[Category: enoyl coa]]
-[[Category: fatty acid synthesis]]
-[[Category: perioxisome]]
-[[Category: sgc]]
-[[Category: short-chain dehydrogenases/reductase]]
-[[Category: structural genomic]]
-[[Category: structural genomics consortium]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:28:45 2008''