4uct: Difference between revisions

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-'''Unreleased structure'''
-The entry 4uct is ON HOLD  until Paper Publication
+==Fragment bound to H.influenza NAD dependent DNA ligase==
+<StructureSection load='4uct' size='340' side='right'caption='[[4uct]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4uct]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCT FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [https://pdbe.org/4uct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [https://www.ebi.ac.uk/pdbsum/4uct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uct ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
-Authors: Hale, M., Brassington, C., Carcanague, D., Embrey, K., Eyermann, C.J., Giacobbe, R.A., Gingipali, L., Gowravaram, M., Harang, J., Howard, T., Ioannidis, G., Jahic, H., Kutschke, A., Laganas, V.A., Loch, J., Miller, M.D., Murphy-Benenato, K.E., Oguto, H., Otterbein, L., Patel, S.J., Shapiro, A.B., Boriack-Sjodin, P.A.
+==See Also==
+*[[DNA ligase 3D structures|DNA ligase 3D structures]]
-Description: Fragment bound to H.influenza NAD dependent DNA ligase
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Loch, J]]
+[[Category: Haemophilus influenzae]]
-[[Category: Embrey, K]]
+[[Category: Large Structures]]
-[[Category: Miller, M.D]]
+[[Category: Boriack-Sjodin PA]]
-[[Category: Boriack-Sjodin, P.A]]
+[[Category: Brassington C]]
-[[Category: Eyermann, C.J]]
+[[Category: Carcanague D]]
-[[Category: Gowravaram, M]]
+[[Category: Embrey K]]
-[[Category: Hale, M]]
+[[Category: Eyermann CJ]]
-[[Category: Otterbein, L]]
+[[Category: Giacobbe RA]]
-[[Category: Howard, T]]
+[[Category: Gingipali L]]
-[[Category: Shapiro, A.B]]
+[[Category: Gowravaram M]]
-[[Category: Gingipali, L]]
+[[Category: Hale M]]
-[[Category: Laganas, V.A]]
+[[Category: Harang J]]
-[[Category: Jahic, H]]
+[[Category: Howard T]]
-[[Category: Murphy-Benenato, K.E]]
+[[Category: Ioannidis G]]
-[[Category: Kutschke, A]]
+[[Category: Jahic H]]
-[[Category: Brassington, C]]
+[[Category: Kutschke A]]
-[[Category: Carcanague, D]]
+[[Category: Laganas VA]]
-[[Category: Patel, S.J]]
+[[Category: Loch J]]
-[[Category: Oguto, H]]
+[[Category: Miller MD]]
-[[Category: Ioannidis, G]]
+[[Category: Murphy-Benenato KE]]
-[[Category: Harang, J]]
+[[Category: Oguto H]]
-[[Category: Giacobbe, R.A]]
+[[Category: Otterbein L]]
+[[Category: Patel SJ]]
+[[Category: Shapiro AB]]