4tld: Difference between revisions

Latest revision as of 12:00, 20 March 2024

Crystal structure of N-terminal C1 domain of KaiCCrystal structure of N-terminal C1 domain of KaiC

Structural highlights

4tld is a 6 chain structure with sequence from Synechococcus elongatus PCC 7942 = FACHB-805. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.949Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KAIC_SYNE7 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.^[1] ^[2]

References

↑ Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T. Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria. Science. 1998 Sep 4;281(5382):1519-23. PMID:9727980
↑ Nakahira Y, Katayama M, Miyashita H, Kutsuna S, Iwasaki H, Oyama T, Kondo T. Global gene repression by KaiC as a master process of prokaryotic circadian system. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):881-5. Epub 2004 Jan 6. PMID:14709675 doi:10.1073/pnas.0307411100

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OCA

[1] Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T. Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria. Science. 1998 Sep 4;281(5382):1519-23. PMID:9727980

[2] Nakahira Y, Katayama M, Miyashita H, Kutsuna S, Iwasaki H, Oyama T, Kondo T. Global gene repression by KaiC as a master process of prokaryotic circadian system. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):881-5. Epub 2004 Jan 6. PMID:14709675 doi:10.1073/pnas.0307411100

[1]

[2]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4tld is ON HOLD  until Paper Publication
+==Crystal structure of N-terminal C1 domain of KaiC==
+<StructureSection load='4tld' size='340' side='right'caption='[[4tld]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4tld]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_7942_=_FACHB-805 Synechococcus elongatus PCC 7942 = FACHB-805]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TLD FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.949&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tld OCA], [https://pdbe.org/4tld PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tld RCSB], [https://www.ebi.ac.uk/pdbsum/4tld PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tld ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KAIC_SYNE7 KAIC_SYNE7] Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.<ref>PMID:9727980</ref> <ref>PMID:14709675</ref>
-Authors: Abe, J., Akiyama, S.
+==See Also==
+*[[Circadian clock protein 3D structures|Circadian clock protein 3D structures]]
-Description:
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Abe, J]]
+__TOC__
-[[Category: Akiyama, S]]
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Synechococcus elongatus PCC 7942 = FACHB-805]]
+[[Category: Abe J]]
+[[Category: Akiyama S]]
+[[Category: Hiyama TB]]
+[[Category: Mukaiyama A]]
+[[Category: Son S]]

4tld: Difference between revisions

Latest revision as of 12:00, 20 March 2024

Crystal structure of N-terminal C1 domain of KaiCCrystal structure of N-terminal C1 domain of KaiC

Structural highlights

Function

See Also

References

Contents

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4tld: Difference between revisions

Latest revision as of 12:00, 20 March 2024

Crystal structure of N-terminal C1 domain of KaiCCrystal structure of N-terminal C1 domain of KaiC

Structural highlights

Function

See Also

References

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