4kyt: Difference between revisions

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==The structure of superinhibitory phospholamban bound to the calcium pump SERCA1a==
==The structure of superinhibitory phospholamban bound to the calcium pump SERCA1a==
<StructureSection load='4kyt' size='340' side='right' caption='[[4kyt]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
<StructureSection load='4kyt' size='340' side='right'caption='[[4kyt]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kyt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Canfa Canfa] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KYT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KYT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kyt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KYT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.833&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANFA])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kyt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kyt RCSB], [http://www.ebi.ac.uk/pdbsum/4kyt PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kyt OCA], [https://pdbe.org/4kyt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kyt RCSB], [https://www.ebi.ac.uk/pdbsum/4kyt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kyt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PPLA_CANFA PPLA_CANFA]] Phospholamban has been postulated to regulate the activity of the calcium pump of cardiac sarcoplasmic reticulum.  
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4kyt" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phospholamban|Phospholamban]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Canfa]]
[[Category: Canis lupus familiaris]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Akin, B L]]
[[Category: Akin BL]]
[[Category: Hurley, T D]]
[[Category: Hurley TD]]
[[Category: Jones, L R]]
[[Category: Jones LR]]
[[Category: Calcium pump]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: P-type atpase]]
[[Category: Transmembrane helice]]

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