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[[Image:1x0a.gif|left|200px]]


{{Structure
==Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8==
|PDB= 1x0a |SIZE=350|CAPTION= <scene name='initialview01'>1x0a</scene>, resolution 2.00&Aring;
<StructureSection load='1x0a' size='340' side='right'caption='[[1x0a]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
<table><tr><td colspan='2'>[[1x0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X0A FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x0a OCA], [https://pdbe.org/1x0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x0a RCSB], [https://www.ebi.ac.uk/pdbsum/1x0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x0a ProSAT], [https://www.topsan.org/Proteins/RSGI/1x0a TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q53W84_THET8 Q53W84_THET8]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x0/1x0a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x0a ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8'''
==See Also==
 
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1X0A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA].
[[Category: Large Structures]]
[[Category: L-lactate dehydrogenase]]
[[Category: Thermus thermophilus HB8]]
[[Category: Single protein]]
[[Category: Kunishima N]]
[[Category: Thermus thermophilus]]
[[Category: Mizutani H]]
[[Category: Kunishima, N.]]
[[Category: Mizutani, H.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: FMT]]
[[Category: NA]]
[[Category: malate dehydrogenase]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:03:41 2008''

Latest revision as of 11:03, 25 October 2023

Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8

Structural highlights

1x0a is a 1 chain structure with sequence from Thermus thermophilus HB8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q53W84_THET8

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1x0a, resolution 2.00Å

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OCA
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