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[[Image:1wy7.gif|left|200px]]


{{Structure
==crystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshii==
|PDB= 1wy7 |SIZE=350|CAPTION= <scene name='initialview01'>1wy7</scene>, resolution 2.2&Aring;
<StructureSection load='1wy7' size='340' side='right'caption='[[1wy7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
<table><tr><td colspan='2'>[[1wy7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WY7 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE= PH1948 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy7 OCA], [https://pdbe.org/1wy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wy7 RCSB], [https://www.ebi.ac.uk/pdbsum/1wy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wy7 ProSAT]</span></td></tr>
 
</table>
'''crystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshii'''
== Function ==
 
[https://www.uniprot.org/uniprot/O59611_PYRHO O59611_PYRHO]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1WY7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY7 OCA].  
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wy/1wy7_consurf.spt"</scriptWhenChecked>
Crystal structure of the putative RNA methyltransferase PH1948 from Pyrococcus horikoshii, in complex with the copurified S-adenosyl-L-homocysteine., Gao YG, Yao M, Yong Z, Tanaka I, Proteins. 2005 Dec 1;61(4):1141-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16245322 16245322]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Pyrococcus horikoshii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Gao, Y G.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wy7 ConSurf].
[[Category: Tanaka, I.]]
<div style="clear:both"></div>
[[Category: Yao, M.]]
__TOC__
[[Category: SAH]]
</StructureSection>
[[Category: methyltransferase fold]]
[[Category: Large Structures]]
[[Category: seven-stranded beta sheet]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: structural genomic]]
[[Category: Gao YG]]
 
[[Category: Tanaka I]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:03:02 2008''
[[Category: Yao M]]

Latest revision as of 16:53, 9 May 2024

crystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshiicrystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshii

Structural highlights

1wy7 is a 4 chain structure with sequence from Pyrococcus horikoshii OT3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O59611_PYRHO

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1wy7, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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