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==Crystal structure of recombinant human annexin IV==
==Crystal structure of recombinant human annexin IV==
<StructureSection load='2zoc' size='340' side='right' caption='[[2zoc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2zoc' size='340' side='right'caption='[[2zoc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zoc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZOC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zoc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zoc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zoc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zoc RCSB], [http://www.ebi.ac.uk/pdbsum/2zoc PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zoc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zoc OCA], [https://pdbe.org/2zoc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zoc RCSB], [https://www.ebi.ac.uk/pdbsum/2zoc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zoc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ANXA4_HUMAN ANXA4_HUMAN]] Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis (By similarity).  
[https://www.uniprot.org/uniprot/ANXA4_HUMAN ANXA4_HUMAN] Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zoc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zoc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zoc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Annexin|Annexin]]
*[[Annexin 3D structures|Annexin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aikawa, K]]
[[Category: Large Structures]]
[[Category: Fushinobu-Okushi, N]]
[[Category: Aikawa K]]
[[Category: Kaneko-Kanzaki, Y]]
[[Category: Fushinobu-Okushi N]]
[[Category: Konno, M]]
[[Category: Kaneko-Kanzaki Y]]
[[Category: Mochizuki, K]]
[[Category: Konno M]]
[[Category: Satoh, A]]
[[Category: Mochizuki K]]
[[Category: Uchikaw, E]]
[[Category: Satoh A]]
[[Category: Annexin]]
[[Category: Uchikaw E]]
[[Category: Calcium/phospholipid-binding]]
[[Category: Helix]]
[[Category: Lipid binding protein]]
[[Category: Metal binding protein]]

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