3ep0: Difference between revisions

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==Methyltransferase domain of human PR domain-containing protein 12==
==Methyltransferase domain of human PR domain-containing protein 12==
<StructureSection load='3ep0' size='340' side='right' caption='[[3ep0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3ep0' size='340' side='right'caption='[[3ep0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ep0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EP0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ep0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EP0 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDM12, PFM9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ep0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ep0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ep0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ep0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ep0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ep0 OCA], [https://pdbe.org/3ep0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ep0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ep0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ep0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRD12_HUMAN PRD12_HUMAN]] May be involved in transcriptional regulation.  
[https://www.uniprot.org/uniprot/PRD12_HUMAN PRD12_HUMAN] May be involved in transcriptional regulation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/3ep0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/3ep0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ep0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Amaya, M F]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Amaya MF]]
[[Category: Botchkarev, A]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Botchkarev A]]
[[Category: Edwards, A M]]
[[Category: Bountra C]]
[[Category: Loppnau, P]]
[[Category: Edwards AM]]
[[Category: Min, J]]
[[Category: Loppnau P]]
[[Category: Plotnikov, A N]]
[[Category: Min J]]
[[Category: Structural genomic]]
[[Category: Plotnikov AN]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Wu, H]]
[[Category: Wu H]]
[[Category: Zeng, H]]
[[Category: Zeng H]]
[[Category: Dna-binding]]
[[Category: Metal-binding]]
[[Category: Nucleus]]
[[Category: Pr domain zinc finger protein 12]]
[[Category: Pr domain-containing protein 12]]
[[Category: Sgc]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transferase]]
[[Category: Zinc-finger]]

Latest revision as of 09:30, 6 September 2023

Methyltransferase domain of human PR domain-containing protein 12Methyltransferase domain of human PR domain-containing protein 12

Structural highlights

3ep0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRD12_HUMAN May be involved in transcriptional regulation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3ep0, resolution 2.10Å

Drag the structure with the mouse to rotate

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OCA