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==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-methyl-UMP==
==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-methyl-UMP==
<StructureSection load='3wjw' size='340' side='right' caption='[[3wjw]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
<StructureSection load='3wjw' size='340' side='right'caption='[[3wjw]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wjw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WJW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wjw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U6M:6-METHYLURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>U6M</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wjx|3wjx]], [[3wjy|3wjy]], [[3wjz|3wjz]], [[3wk0|3wk0]], [[3wk1|3wk1]], [[3wk2|3wk2]], [[3wk3|3wk3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U6M:6-METHYLURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>U6M</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjw OCA], [https://pdbe.org/3wjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wjw RCSB], [https://www.ebi.ac.uk/pdbsum/3wjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjw ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wjw RCSB], [http://www.ebi.ac.uk/pdbsum/3wjw PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3wjw" style="background-color:#fffaf0;"></div>
==See Also==
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metth]]
[[Category: Large Structures]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
[[Category: Fujihashi, M]]
[[Category: Fujihashi M]]
[[Category: Kuroda, S]]
[[Category: Kuroda S]]
[[Category: Miki, K]]
[[Category: Miki K]]
[[Category: Pai, E F]]
[[Category: Pai EF]]
[[Category: Decarboxylase]]
[[Category: Lyase]]
[[Category: Protein-ligand complex]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Tim barrel]]

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