3tl8: Difference between revisions

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 ==The AvrPtoB-BAK1 complex reveals two structurally similar kinaseinteracting domains in a single type III effector==
-<StructureSection load='3tl8' size='340' side='right' caption='[[3tl8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+<StructureSection load='3tl8' size='340' side='right'caption='[[3tl8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3tl8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._tomato Pseudomonas syringae pv. tomato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TL8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3tl8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._tomato Pseudomonas syringae pv. tomato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TL8 FirstGlance]. <br>
-</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAK1, ELG, SERK3, At4g33430, F17M5.190 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana]), hopAB2, avrPtoB, PSPTO_3087 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=323 Pseudomonas syringae pv. tomato])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tl8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tl8 RCSB], [http://www.ebi.ac.uk/pdbsum/3tl8 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tl8 OCA], [https://pdbe.org/3tl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tl8 RCSB], [https://www.ebi.ac.uk/pdbsum/3tl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tl8 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/BAK1_ARATH BAK1_ARATH] Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1-BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) via its interaction with FLS2 and the phosphorylation of BIK1. Involved in programmed cell death (PCD) control. Positively regulates the BR-dependent plant growth pathway and negatively regulates the BR-independent cell-death pathway.<ref>PMID:17600708</ref> <ref>PMID:17583510</ref> <ref>PMID:18694562</ref> <ref>PMID:18667726</ref> <ref>PMID:19124768</ref> <ref>PMID:20018402</ref> <ref>PMID:20404519</ref> <ref>PMID:21350342</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 3tl8" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Avirulence protein|Avirulence protein]]
+*[[Avirulence protein 3D structures|Avirulence protein 3D structures]]
 == References ==
 <references/>
@@ Line 23: / Line 27: @@
 </StructureSection>
 [[Category: Arabidopsis thaliana]]
+[[Category: Large Structures]]
 [[Category: Pseudomonas syringae pv. tomato]]
-[[Category: Chai, J]]
+[[Category: Chai J]]
-[[Category: Cheng, W]]
+[[Category: Cheng W]]
-[[Category: Gao, H]]
+[[Category: Gao H]]
-[[Category: Bacterial pathogenesis]]
-[[Category: Pamp-triggered immunity]]
-[[Category: Plant immunity]]
-[[Category: Pseudomonas syringae]]
-[[Category: Solanum lycopersicum]]
-[[Category: Transferase-ligase complex]]