4u3u: Difference between revisions

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 ==Crystal structure of Cycloheximide bound to the yeast 80S ribosome==
-<StructureSection load='4u3u' size='340' side='right' caption='[[4u3u]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+<StructureSection load='4u3u' size='340' side='right'caption='[[4u3u]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4u3u]] is a 162 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_atcc_204508_/_s288c Saccharomyces cerevisiae atcc 204508 / s288c]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4uke 4uke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3U FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4u3u]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4uk9 4uk9], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4uka 4uka], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukb 4ukb], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukc 4ukc] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4uke 4uke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3U FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HE:4-{(2R)-2-[(1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL}PIPERIDINE-2,6-DIONE'>3HE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3HE:4-{(2R)-2-[(1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL}PIPERIDINE-2,6-DIONE'>3HE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uk9|4uk9]], [[4uka|4uka]], [[4ukb|4ukb]], [[4ukc|4ukc]], [[4uke|4uke]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3u OCA], [https://pdbe.org/4u3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3u RCSB], [https://www.ebi.ac.uk/pdbsum/4u3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3u ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u3u RCSB], [http://www.ebi.ac.uk/pdbsum/4u3u PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/RSSA1_YEAST RSSA1_YEAST] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.<ref>PMID:9973221</ref> <ref>PMID:14627813</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 16: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4u3u" style="background-color:#fffaf0;"></div>
 ==See Also==
 *[[Ribosome 3D structures|Ribosome 3D structures]]
+*[[3D sructureseceptor for activated protein kinase C 1|3D sructureseceptor for activated protein kinase C 1]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Saccharomyces cerevisiae atcc 204508 / s288c]]
+[[Category: Large Structures]]
-[[Category: Loubresse, N Garreau de]]
+[[Category: Saccharomyces cerevisiae S288C]]
-[[Category: Prokhorova, I]]
+[[Category: Garreau de Loubresse N]]
-[[Category: Yusupov, M]]
+[[Category: Prokhorova I]]
-[[Category: Yusupova, G]]
+[[Category: Yusupov M]]
-[[Category: Antibiotic]]
+[[Category: Yusupova G]]
-[[Category: Eukaryote]]
-[[Category: Inhibitor]]
-[[Category: Ribosome]]
-[[Category: Rna-protein complex]]
-[[Category: Translation]]