1og0: Difference between revisions

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[[Image:1og0.gif|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF THE MUTANT G226S OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE==
|PDB= 1og0 |SIZE=350|CAPTION= <scene name='initialview01'>1og0</scene>, resolution 2.7&Aring;
<StructureSection load='1og0' size='340' side='right'caption='[[1og0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:PHE+Binding+Site+For+Chain+H'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>
<table><tr><td colspan='2'>[[1og0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OG0 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.5.1.54 Transferred entry: 2.5.1.54], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.15 4.1.2.15]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1og0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1og0 OCA], [https://pdbe.org/1og0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1og0 RCSB], [https://www.ebi.ac.uk/pdbsum/1og0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1og0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROG_YEAST AROG_YEAST] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/1og0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1og0 ConSurf].
<div style="clear:both"></div>


'''CRYSTAL STRUCTURE OF THE MUTANT G226S OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE'''
==See Also==
 
*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1OG0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OG0 OCA].
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Braus GH]]
[[Category: Transferred entry: 2 5.1 54]]
[[Category: Heinrich G]]
[[Category: Braus, G.]]
[[Category: Koenig V]]
[[Category: Heinrich, G.]]
[[Category: Pfeil A]]
[[Category: Koenig, V.]]
[[Category: Schneider TR]]
[[Category: Pfeil, A.]]
[[Category: Schneider, T R.]]
[[Category: MN]]
[[Category: PHE]]
[[Category: beta-alpha-barrel]]
[[Category: lyase]]
 
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