3znh: Difference between revisions

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OCA

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 ==Crimean Congo Hemorrhagic Fever Virus OTU domain in complex with ubiquitin-propargyl.==
-<StructureSection load='3znh' size='340' side='right' caption='[[3znh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='3znh' size='340' side='right'caption='[[3znh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3znh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cchfi Cchfi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZNH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3znh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crimean-Congo_hemorrhagic_fever_virus_strain_IbAr10200 Crimean-Congo hemorrhagic fever virus strain IbAr10200] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZNH FirstGlance]. <br>
-</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYE:PROP-2-EN-1-AMINE'>AYE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AYE:PROP-2-EN-1-AMINE'>AYE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3znh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3znh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3znh RCSB], [http://www.ebi.ac.uk/pdbsum/3znh PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3znh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3znh OCA], [https://pdbe.org/3znh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3znh RCSB], [https://www.ebi.ac.uk/pdbsum/3znh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3znh ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 3znh" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Thioesterase|Thioesterase]]
+*[[Thioesterase 3D structures|Thioesterase 3D structures]]
-*[[Ubiquitin|Ubiquitin]]
+*[[3D structures of ubiquitin|3D structures of ubiquitin]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Cchfi]]
+[[Category: Crimean-Congo hemorrhagic fever virus strain IbAr10200]]
-[[Category: Ubiquitinyl hydrolase 1]]
+[[Category: Homo sapiens]]
-[[Category: Berlin, I]]
+[[Category: Large Structures]]
-[[Category: Ekkebus, R]]
+[[Category: Berlin I]]
-[[Category: Goerdayal, G]]
+[[Category: Ekkebus R]]
-[[Category: Heck, A J.R]]
+[[Category: Goerdayal G]]
-[[Category: Komander, D]]
+[[Category: Heck AJR]]
-[[Category: Kulathu, Y]]
+[[Category: Komander D]]
-[[Category: Neefjes, J]]
+[[Category: Kulathu Y]]
-[[Category: Ovaa, H]]
+[[Category: Neefjes J]]
-[[Category: Scholten, A]]
+[[Category: Ovaa H]]
-[[Category: DeJong, A]]
+[[Category: Scholten A]]
-[[Category: VanKasteren, S I]]
+[[Category: DeJong A]]
-[[Category: Deubiquitinase]]
+[[Category: VanKasteren SI]]
-[[Category: Hydrolase-signaling protein complex]]