3p16: Difference between revisions
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==Crystal structure of DNA polymerase III sliding clamp== | ==Crystal structure of DNA polymerase III sliding clamp== | ||
<StructureSection load='3p16' size='340' side='right' caption='[[3p16]], [[Resolution|resolution]] 2.89Å' scene=''> | <StructureSection load='3p16' size='340' side='right'caption='[[3p16]], [[Resolution|resolution]] 2.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3p16]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3p16]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P16 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.89Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p16 OCA], [https://pdbe.org/3p16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p16 RCSB], [https://www.ebi.ac.uk/pdbsum/3p16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p16 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DPO3B_MYCTU DPO3B_MYCTU] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3p16" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[DNA polymerase|DNA polymerase]] | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Bi | [[Category: Bi LJ]] | ||
[[Category: Chen | [[Category: Chen YY]] | ||
[[Category: Gui | [[Category: Gui WJ]] | ||
[[Category: Jiang | [[Category: Jiang T]] | ||
[[Category: Lin | [[Category: Lin SQ]] | ||
[[Category: Zhang | [[Category: Zhang XE]] | ||