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==Crystal structure of monomeric isocitrate dehydrogenase from Corynebacterium glutamicum in complex with NADP==
==Crystal structure of monomeric isocitrate dehydrogenase from Corynebacterium glutamicum in complex with NADP==
<StructureSection load='3mbc' size='340' side='right' caption='[[3mbc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3mbc' size='340' side='right'caption='[[3mbc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3mbc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MBC FirstGlance]. <br>
<table><tr><td colspan='2'>[[3mbc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MBC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b0t|2b0t]], [[1itw|1itw]], [[1j1w|1j1w]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mbc OCA], [https://pdbe.org/3mbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mbc RCSB], [https://www.ebi.ac.uk/pdbsum/3mbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mbc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mbc RCSB], [http://www.ebi.ac.uk/pdbsum/3mbc PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IDH_CORGL IDH_CORGL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3mbc" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Corynebacterium glutamicum]]
[[Category: Corynebacterium glutamicum ATCC 13032]]
[[Category: Aich, S]]
[[Category: Large Structures]]
[[Category: Delbaere, L T.J]]
[[Category: Aich S]]
[[Category: Sheldrick, G M]]
[[Category: Delbaere LTJ]]
[[Category: Sidhu, N S]]
[[Category: Sheldrick GM]]
[[Category: Apoenzyme]]
[[Category: Sidhu NS]]
[[Category: Glyoxylate bypass]]
[[Category: Holoenzyme]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Nadp]]
[[Category: Open conformation]]
[[Category: Oxidoreductase]]
[[Category: Tricarboxylic acid cycle]]

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