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==Crystal structure of unliganded yeast PDE1==
==Crystal structure of unliganded yeast PDE1==
<StructureSection load='4ojv' size='340' side='right' caption='[[4ojv]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
<StructureSection load='4ojv' size='340' side='right'caption='[[4ojv]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ojv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OJV FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ojv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OJV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ojx|4ojx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ojv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojv OCA], [https://pdbe.org/4ojv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ojv RCSB], [https://www.ebi.ac.uk/pdbsum/4ojv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ojv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ojv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ojv RCSB], [http://www.ebi.ac.uk/pdbsum/4ojv PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDE1_YEAST PDE1_YEAST] Controls the level of cAMP in yeast cells, together with the high-affinity cAMP phosphodiesterase (PDE2).
==See Also==
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Large Structures]]
[[Category: Cui, W]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Huang, M]]
[[Category: Cui W]]
[[Category: Ke, H]]
[[Category: Huang M]]
[[Category: Robinson, H]]
[[Category: Ke H]]
[[Category: Tian, Y]]
[[Category: Robinson H]]
[[Category: Wan, Y]]
[[Category: Tian Y]]
[[Category: Wang, Y]]
[[Category: Wan Y]]
[[Category: Cgmp and camp]]
[[Category: Wang Y]]
[[Category: Dual specificity]]
[[Category: Hydrolase]]
[[Category: Phosphodiesterase]]
[[Category: Yeast pde]]

Latest revision as of 15:40, 1 March 2024

Crystal structure of unliganded yeast PDE1Crystal structure of unliganded yeast PDE1

Structural highlights

4ojv is a 1 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.31Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDE1_YEAST Controls the level of cAMP in yeast cells, together with the high-affinity cAMP phosphodiesterase (PDE2).

See Also

4ojv, resolution 1.31Å

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