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==Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with D-xylulofuranose==
==Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with D-xylulofuranose==
<StructureSection load='3ctp' size='340' side='right' caption='[[3ctp]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='3ctp' size='340' side='right'caption='[[3ctp]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ctp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Alkaliphilus_metalliredigens Alkaliphilus metalliredigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CTP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ctp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkaliphilus_metalliredigens_QYMF Alkaliphilus metalliredigens QYMF]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CTP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XLF:BETA-D-XYLULOFURANOSE'>XLF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Amet_0586 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208226 Alkaliphilus metalliredigens])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XLF:BETA-D-XYLULOFURANOSE'>XLF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ctp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ctp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ctp RCSB], [http://www.ebi.ac.uk/pdbsum/3ctp PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ctp TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ctp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ctp OCA], [https://pdbe.org/3ctp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ctp RCSB], [https://www.ebi.ac.uk/pdbsum/3ctp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ctp ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ctp TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A6TKU5_ALKMQ A6TKU5_ALKMQ]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ct/3ctp_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ct/3ctp_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ctp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alkaliphilus metalliredigens]]
[[Category: Alkaliphilus metalliredigens QYMF]]
[[Category: Almo, S C]]
[[Category: Large Structures]]
[[Category: Burley, S K]]
[[Category: Almo SC]]
[[Category: Malashkevich, V N]]
[[Category: Burley SK]]
[[Category: Meyer, A]]
[[Category: Malashkevich VN]]
[[Category: Structural genomic]]
[[Category: Meyer A]]
[[Category: Sauder, J M]]
[[Category: Sauder JM]]
[[Category: Toro, R]]
[[Category: Toro R]]
[[Category: Wasserman, S R]]
[[Category: Wasserman SR]]
[[Category: D-xylulofuranose]]
[[Category: Dna-binding]]
[[Category: L-xylulose]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
[[Category: Transcriptional regulator]]

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