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==Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas Gingivalis==
==Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas Gingivalis==
<StructureSection load='2im5' size='340' side='right' caption='[[2im5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2im5' size='340' side='right'caption='[[2im5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2im5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IM5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IM5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2im5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IM5 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pncB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=837 Porphyromonas gingivalis])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2im5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2im5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2im5 RCSB], [http://www.ebi.ac.uk/pdbsum/2im5 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2im5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2im5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2im5 OCA], [https://pdbe.org/2im5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2im5 RCSB], [https://www.ebi.ac.uk/pdbsum/2im5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2im5 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2im5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q7MXV0_PORGI Q7MXV0_PORGI] Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.[HAMAP-Rule:MF_00570]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/2im5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/2im5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2im5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Porphyromonas gingivalis]]
[[Category: Porphyromonas gingivalis]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Fedorov, A A]]
[[Category: Fedorov AA]]
[[Category: Fedorov, E V]]
[[Category: Fedorov EV]]
[[Category: Structural genomic]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Phosphoribosyltransferase]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]

Latest revision as of 12:03, 21 February 2024

Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas GingivalisCrystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas Gingivalis

Structural highlights

2im5 is a 4 chain structure with sequence from Porphyromonas gingivalis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q7MXV0_PORGI Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.[HAMAP-Rule:MF_00570]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2im5, resolution 2.20Å

Drag the structure with the mouse to rotate

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OCA
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