4wu9: Difference between revisions

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-'''Unreleased structure'''
-The entry 4wu9 is ON HOLD
+==Structure of cisPtNAP-NCP145==
+<StructureSection load='4wu9' size='340' side='right'caption='[[4wu9]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-Authors: Chua, E.Y.D., Davey, G.E., Chin, C.F., Droge, P., Ang, W.H., Davey, C.A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4wu9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WU9 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CX8:[2-{3-[(2-{[2-(AMINO-KAPPAN)ETHYL]AMINO-KAPPAN}ETHYL)AMINO-KAPPAN]PROPYL}-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONATO(3-)]PLATINUM'>CX8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wu9 OCA], [https://pdbe.org/4wu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wu9 RCSB], [https://www.ebi.ac.uk/pdbsum/4wu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wu9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Xenopus laevis]]
+[[Category: Ang WH]]
+[[Category: Chin CF]]
+[[Category: Chua EYD]]
+[[Category: Davey CA]]
+[[Category: Davey GE]]
+[[Category: Droge P]]