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[[Image:1k6f.jpg|left|200px]]


{{Structure
==Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3==
|PDB= 1k6f |SIZE=350|CAPTION= <scene name='initialview01'>1k6f</scene>, resolution 1.3&Aring;
<StructureSection load='1k6f' size='340' side='right'caption='[[1k6f]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1k6f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saimiriine_gammaherpesvirus_2 Saimiriine gammaherpesvirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6F FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6f OCA], [https://pdbe.org/1k6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6f RCSB], [https://www.ebi.ac.uk/pdbsum/1k6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6f ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q80BK4_SHV2 Q80BK4_SHV2]


'''Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3'''
==See Also==
 
*[[Collagen 3D structures|Collagen 3D structures]]
 
__TOC__
==Overview==
</StructureSection>
The first report of the full-length structure of the collagen-like polypeptide [(Pro-Pro-Gly)(10)](3) is given. This structure was obtained from crystals grown in a microgravity environment, which diffracted up to 1.3 A, using synchrotron radiation. The final model, which was refined to an R(factor) of 0.18, is the highest-resolution description of a collagen triple helix reported to date. This structure provides clues regarding a series of aspects related to collagen triple helix structure and assembly. The strict dependence of proline puckering on the position inside the Pro-Pro-Gly triplets and the correlation between backbone and side chain dihedral angles support the propensity-based mechanism of triple helix stabilization/destabilization induced by hydroxyproline. Furthermore, the analysis of [(Pro-Pro-Gly)(10)](3) packing, which is governed by electrostatic interactions, suggests that charges may act as locking features in the axial organization of triple helices in the collagen fibrils.
[[Category: Large Structures]]
 
[[Category: Saimiriine gammaherpesvirus 2]]
==About this Structure==
[[Category: Berisio R]]
1K6F is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6F OCA].
[[Category: Mazzarella L]]
 
[[Category: Vitagliano L]]
==Reference==
[[Category: Zagari A]]
Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)(10)](3)., Berisio R, Vitagliano L, Mazzarella L, Zagari A, Protein Sci. 2002 Feb;11(2):262-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11790836 11790836]
[[Category: Protein complex]]
[[Category: Berisio, R.]]
[[Category: Mazzarella, L.]]
[[Category: Vitagliano, L.]]
[[Category: Zagari, A]]
[[Category: amino acid preference]]
[[Category: collagen stability]]
[[Category: puckering]]
[[Category: triple helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:13:15 2008''

Latest revision as of 10:44, 7 February 2024

Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3

Structural highlights

1k6f is a 6 chain structure with sequence from Saimiriine gammaherpesvirus 2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q80BK4_SHV2

See Also

1k6f, resolution 1.30Å

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