4wj0: Difference between revisions
New page: '''Unreleased structure''' The entry 4wj0 is ON HOLD Authors: Petit, P, Brown, G., Savchenko, A., Yakunin, A.F. Description: Structure of PH1245, a cas1 from Pyrococcus horikoshii |
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==Structure of PH1245, a cas1 from Pyrococcus horikoshii== | |||
<StructureSection load='4wj0' size='340' side='right'caption='[[4wj0]], [[Resolution|resolution]] 2.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3pv9 3pv9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WJ0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wj0 OCA], [https://pdbe.org/4wj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wj0 RCSB], [https://www.ebi.ac.uk/pdbsum/4wj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wj0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAS1_PYRHO CAS1_PYRHO] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | |||
==See Also== | |||
*[[Endonuclease 3D structures|Endonuclease 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus horikoshii OT3]] | |||
[[Category: Brown G]] | |||
[[Category: Petit P]] | |||
[[Category: Savchenko A]] | |||
[[Category: Yakunin AF]] | |||