2yx8: Difference between revisions

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 ==Crystal structure of the extracellular domain of human RAMP1==
-<StructureSection load='2yx8' size='340' side='right' caption='[[2yx8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='2yx8' size='340' side='right'caption='[[2yx8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2yx8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YX8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YX8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2yx8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YX8 FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAMP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAMP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yx8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yx8 RCSB], [http://www.ebi.ac.uk/pdbsum/2yx8 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yx8 TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yx8 OCA], [https://pdbe.org/2yx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yx8 TOPSAN]</span></td></tr>
-<table>
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/RAMP1_HUMAN RAMP1_HUMAN]] Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.<ref>PMID:9620797</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yx8_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yx8_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yx8 ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 25: / Line 28: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2yx8" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Homo sapiens]]
+[[Category: Human]]
-[[Category: Kukimoto-Niino, M.]]
+[[Category: Large Structures]]
-[[Category: Kusano, S.]]
+[[Category: Kukimoto-Niino, M]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Kusano, S]]
-[[Category: Shindo, T.]]
+[[Category: Structural genomic]]
-[[Category: Shirouzu, M.]]
+[[Category: Shindo, T]]
-[[Category: Yokoyama, S.]]
+[[Category: Shirouzu, M]]
+[[Category: Yokoyama, S]]
 [[Category: Adrenomedulin]]
 [[Category: Bibn4096b]]
@@ Line 50: / Line 55: @@
 [[Category: Nppsfa]]
 [[Category: Protein transport]]
-[[Category: Riken structural genomics/proteomics initiative]]
 [[Category: Rsgi]]
-[[Category: Structural genomic]]
 [[Category: Trafficking]]
 [[Category: Transmembrane]]