2rbr: Difference between revisions

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 ==2-phenoxyethanol in complex with T4 lysozyme L99A/M102Q==
-<StructureSection load='2rbr' size='340' side='right' caption='[[2rbr]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
+<StructureSection load='2rbr' size='340' side='right'caption='[[2rbr]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2rbr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RBR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2rbr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RBR FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=268:2-PHENOXYETHANOL'>268</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.433&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[181l|181l]], [[1lgu|1lgu]], [[2ray|2ray]], [[2raz|2raz]], [[2rb0|2rb0]], [[2rb1|2rb1]], [[2rb2|2rb2]], [[2rbn|2rbn]], [[2rbo|2rbo]], [[2rbp|2rbp]], [[2rbq|2rbq]], [[2ras|2ras]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=268:2-PHENOXYETHANOL'>268</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rbr OCA], [https://pdbe.org/2rbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rbr RCSB], [https://www.ebi.ac.uk/pdbsum/2rbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rbr ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
+</table>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rbr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rbr RCSB], [http://www.ebi.ac.uk/pdbsum/2rbr PDBsum]</span></td></tr>
+== Function ==
-<table>
+[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 17: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2rbr" style="background-color:#fffaf0;"></div>
 ==See Also==
@@ Line 24: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Enterobacteria phage t4]]
+[[Category: Escherichia virus T4]]
-[[Category: Lysozyme]]
+[[Category: Large Structures]]
-[[Category: Boyce, S E.]]
+[[Category: Boyce SE]]
-[[Category: Graves, A P.]]
+[[Category: Graves AP]]
-[[Category: Shoichet, B K.]]
+[[Category: Shoichet BK]]
-[[Category: Hydrolase]]
-[[Category: Protein cavity]]