1x05: Difference between revisions

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==Solution structure of the C-terminal PH domain of human pleckstrin==
==Solution structure of the C-terminal PH domain of human pleckstrin==
<StructureSection load='1x05' size='340' side='right' caption='[[1x05]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1x05' size='340' side='right'caption='[[1x05]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1x05]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X05 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1x05]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X05 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x05 RCSB], [http://www.ebi.ac.uk/pdbsum/1x05 PDBsum], [http://www.topsan.org/Proteins/RSGI/1x05 TOPSAN]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x05 OCA], [https://pdbe.org/1x05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x05 RCSB], [https://www.ebi.ac.uk/pdbsum/1x05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x05 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x05 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLEK_HUMAN PLEK_HUMAN] Major protein kinase C substrate of platelets.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x0/1x05_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x0/1x05_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x05 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Inoue, M.]]
[[Category: Large Structures]]
[[Category: Kigawa, T.]]
[[Category: Inoue M]]
[[Category: Koshiba, S.]]
[[Category: Kigawa T]]
[[Category: Li, H.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Li H]]
[[Category: Tomizawa, T.]]
[[Category: Tomizawa T]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Ph domain]]
[[Category: Pleckstrin]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]

Latest revision as of 16:55, 9 May 2024

Solution structure of the C-terminal PH domain of human pleckstrinSolution structure of the C-terminal PH domain of human pleckstrin

Structural highlights

1x05 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PLEK_HUMAN Major protein kinase C substrate of platelets.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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