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==The 2.0 A X-ray structure of Guanylate Kinase from E.coli== | ==The 2.0 A X-ray structure of Guanylate Kinase from E.coli== | ||
<StructureSection load='1s96' size='340' side='right' caption='[[1s96]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1s96' size='340' side='right'caption='[[1s96]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S96 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr><td class="sblockLbl"><b>[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [https://pdbe.org/1s96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB], [https://www.ebi.ac.uk/pdbsum/1s96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s96 ProSAT]</span></td></tr> | |||
<tr | </table> | ||
== Function == | |||
<table> | [https://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s96 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Guanylate kinase|Guanylate kinase]] | *[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Klock | [[Category: Klock HE]] | ||
[[Category: Kreusch | [[Category: Kreusch A]] | ||
[[Category: Lesley | [[Category: Lesley SA]] | ||
[[Category: McMullan | [[Category: McMullan D]] | ||
[[Category: Rodrigues | [[Category: Rodrigues K]] | ||
[[Category: Spraggon | [[Category: Spraggon G]] | ||
[[Category: Vincent | [[Category: Vincent J]] | ||
Latest revision as of 10:26, 9 October 2024
The 2.0 A X-ray structure of Guanylate Kinase from E.coliThe 2.0 A X-ray structure of Guanylate Kinase from E.coli
Structural highlights
FunctionKGUA_ECOLI Essential for recycling GMP and indirectly, cGMP.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences |
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