1v53: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (6 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans== | ==The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans== | ||
<StructureSection load='1v53' size='340' side='right' caption='[[1v53]], [[Resolution|resolution]] 2.85Å' scene=''> | <StructureSection load='1v53' size='340' side='right'caption='[[1v53]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1v53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Weizmannia_coagulans Weizmannia coagulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V53 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v53 OCA], [https://pdbe.org/1v53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v53 RCSB], [https://www.ebi.ac.uk/pdbsum/1v53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v53 ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LEU3_WEICA LEU3_WEICA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v53_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v53_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v53 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| Line 21: | Line 24: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Weizmannia coagulans]] | ||
[[Category: Fujita | [[Category: Fujita K]] | ||
[[Category: Minami | [[Category: Minami H]] | ||
[[Category: Mizui | [[Category: Mizui R]] | ||
[[Category: Nakamura | [[Category: Nakamura S]] | ||
[[Category: Sekiguchi | [[Category: Sekiguchi T]] | ||
[[Category: Suzuki | [[Category: Suzuki K]] | ||
[[Category: Takenaka | [[Category: Takenaka A]] | ||
[[Category: Tsunoda | [[Category: Tsunoda M]] | ||
[[Category: Tsuzaki | [[Category: Tsuzaki S]] | ||
Latest revision as of 10:47, 25 October 2023
The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulansThe crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans
Structural highlights
FunctionLEU3_WEICA Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
| ||||||||||||||||