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==Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin==
==Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin==
<StructureSection load='1j1s' size='340' side='right' caption='[[1j1s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1j1s' size='340' side='right'caption='[[1j1s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1j1s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phytolacca_americana Phytolacca americana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J1S FirstGlance]. <br>
<table><tr><td colspan='2'>[[1j1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytolacca_americana Phytolacca americana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J1S FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMP:FORMYCIN-5-MONOPHOSPHATE'>FMP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j1q|1j1q]], [[1j1r|1j1r]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMP:FORMYCIN-5-MONOPHOSPHATE'>FMP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1s OCA], [https://pdbe.org/1j1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j1s RCSB], [https://www.ebi.ac.uk/pdbsum/1j1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j1s ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j1s RCSB], [http://www.ebi.ac.uk/pdbsum/1j1s PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/RIPS_PHYAM RIPS_PHYAM] Inhibits viral infection of plants, and protein synthesis in vitro.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/1j1s_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/1j1s_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j1s ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Phytolacca americana]]
[[Category: Phytolacca americana]]
[[Category: RRNA N-glycosylase]]
[[Category: Fujii H]]
[[Category: Fujii, H.]]
[[Category: Hidaka A]]
[[Category: Hidaka, A.]]
[[Category: Honjo E]]
[[Category: Honjo, E.]]
[[Category: Kurokawa H]]
[[Category: Kurokawa, H.]]
[[Category: Mikami B]]
[[Category: Mikami, B.]]
[[Category: Monzingo AF]]
[[Category: Monzingo, A F.]]
[[Category: Motoshima H]]
[[Category: Motoshima, H.]]
[[Category: Robertus JD]]
[[Category: Robertus, J D.]]
[[Category: Sato E]]
[[Category: Sato, E.]]
[[Category: Watanabe K]]
[[Category: Watanabe, K.]]
[[Category: Hydrolase]]
[[Category: N-glycosidase]]
[[Category: Pokeweed antiviral protein]]
[[Category: Ribosome-inactivating protein]]

Latest revision as of 11:32, 6 November 2024

Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with FormycinPokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin

Structural highlights

1j1s is a 1 chain structure with sequence from Phytolacca americana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIPS_PHYAM Inhibits viral infection of plants, and protein synthesis in vitro.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1j1s, resolution 2.00Å

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OCA