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==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION== | ==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION== | ||
<StructureSection load='3zyb' size='340' side='right' caption='[[3zyb]], [[Resolution|resolution]] 2.29Å' scene=''> | <StructureSection load='3zyb' size='340' side='right'caption='[[3zyb]], [[Resolution|resolution]] 2.29Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zyb]] is a | <table><tr><td colspan='2'>[[3zyb]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYB FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand= | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PHB:P-HYDROXYBENZOIC+ACID'>PHB</scene></td></tr> | |||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyb OCA], [https://pdbe.org/3zyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyb RCSB], [https://www.ebi.ac.uk/pdbsum/3zyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyb ProSAT]</span></td></tr> | ||
</table> | |||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Large Structures]] | ||
[[Category: Bergmann | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: Cacciarini | [[Category: Synthetic construct]] | ||
[[Category: Camara | [[Category: Bergmann M]] | ||
[[Category: Darbre | [[Category: Cacciarini M]] | ||
[[Category: Garg | [[Category: Camara M]] | ||
[[Category: Hurley | [[Category: Darbre T]] | ||
[[Category: Kadam | [[Category: Garg D]] | ||
[[Category: Nativi | [[Category: Hurley M]] | ||
[[Category: Reymond | [[Category: Kadam RU]] | ||
[[Category: Sattler | [[Category: Nativi C]] | ||
[[Category: Smyth | [[Category: Reymond J-L]] | ||
[[Category: Stocker | [[Category: Sattler M]] | ||
[[Category: Swiderska | [[Category: Smyth AR]] | ||
[[Category: Williams | [[Category: Stocker A]] | ||
[[Category: Swiderska MA]] | |||
[[Category: Williams P]] | |||
Latest revision as of 14:15, 20 December 2023
CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTIONCRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION
Structural highlights
FunctionPA1L_PSEAE D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. See Also |
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