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==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION==
==CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION==
<StructureSection load='3zyb' size='340' side='right' caption='[[3zyb]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
<StructureSection load='3zyb' size='340' side='right'caption='[[3zyb]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zyb]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZYB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zyb]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYB FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PHB:P-HYDROXYBENZOIC+ACID'>PHB</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PHB:P-HYDROXYBENZOIC+ACID'>PHB</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vxj|2vxj]], [[1oko|1oko]], [[1uoj|1uoj]], [[2wyf|2wyf]], [[1l7l|1l7l]], [[3zyf|3zyf]], [[3zyh|3zyh]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyb OCA], [https://pdbe.org/3zyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyb RCSB], [https://www.ebi.ac.uk/pdbsum/3zyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyb ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zyb RCSB], [http://www.ebi.ac.uk/pdbsum/3zyb PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Large Structures]]
[[Category: Bergmann, M.]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Cacciarini, M.]]
[[Category: Synthetic construct]]
[[Category: Camara, M.]]
[[Category: Bergmann M]]
[[Category: Darbre, T.]]
[[Category: Cacciarini M]]
[[Category: Garg, D.]]
[[Category: Camara M]]
[[Category: Hurley, M.]]
[[Category: Darbre T]]
[[Category: Kadam, R U.]]
[[Category: Garg D]]
[[Category: Nativi, C.]]
[[Category: Hurley M]]
[[Category: Reymond, J L.]]
[[Category: Kadam RU]]
[[Category: Sattler, M.]]
[[Category: Nativi C]]
[[Category: Smyth, A R.]]
[[Category: Reymond J-L]]
[[Category: Stocker, A.]]
[[Category: Sattler M]]
[[Category: Swiderska, M A.]]
[[Category: Smyth AR]]
[[Category: Williams, P.]]
[[Category: Stocker A]]
[[Category: Adhesin]]
[[Category: Swiderska MA]]
[[Category: Galactose-specific]]
[[Category: Williams P]]
[[Category: Galactoside]]
[[Category: Glycosphingolipid-antigen]]
[[Category: Sugar binding protein]]

Latest revision as of 14:15, 20 December 2023

CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTIONCRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION

Structural highlights

3zyb is a 11 chain structure with sequence from Pseudomonas aeruginosa PAO1 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.29Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PA1L_PSEAE D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.

See Also

3zyb, resolution 2.29Å

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