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==X-ray structure of NikA in complex with Fe(1R,2R)-N,N'-Bis(2-pyridylmethyl)-N,N'-dicarboxymethyl-1,2-cyclohexanediamine== | ==X-ray structure of NikA in complex with Fe(1R,2R)-N,N'-Bis(2-pyridylmethyl)-N,N'-dicarboxymethyl-1,2-cyclohexanediamine== | ||
<StructureSection load='4dcx' size='340' side='right' caption='[[4dcx]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4dcx' size='340' side='right' caption='[[4dcx]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4dcx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4dcx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DCX FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L2D:{2,2-[(1R,2R)-CYCLOHEXANE-1,2-DIYLBIS{[(PYRIDIN-2-YL-KAPPAN)METHYL]IMINO-KAPPAN}]DIACETATO-KAPPAO(2-)}IRON'>L2D</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L2D:{2,2-[(1R,2R)-CYCLOHEXANE-1,2-DIYLBIS{[(PYRIDIN-2-YL-KAPPAN)METHYL]IMINO-KAPPAN}]DIACETATO-KAPPAO(2-)}IRON'>L2D</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zlq|1zlq]], [[4dcy|4dcy]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zlq|1zlq]], [[4dcy|4dcy]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3476, JW3441, nikA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3476, JW3441, nikA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dcx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dcx RCSB], [http://www.ebi.ac.uk/pdbsum/4dcx PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dcx OCA], [http://pdbe.org/4dcx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dcx RCSB], [http://www.ebi.ac.uk/pdbsum/4dcx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dcx ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NIKA_ECOLI NIKA_ECOLI]] Involved in a nickel transport system, probably represents the nickel binder. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 19: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4dcx" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Ecoli]] | ||
[[Category: Amara, P | [[Category: Amara, P]] | ||
[[Category: Cavazza, C | [[Category: Cavazza, C]] | ||
[[Category: Cherrier, M V | [[Category: Cherrier, M V]] | ||
[[Category: Fontecilla-Camps, J C | [[Category: Fontecilla-Camps, J C]] | ||
[[Category: Girgenti, E | [[Category: Girgenti, E]] | ||
[[Category: Iannello, M | [[Category: Iannello, M]] | ||
[[Category: Marchi-Delapierre, C | [[Category: Marchi-Delapierre, C]] | ||
[[Category: Menage, S | [[Category: Menage, S]] | ||
[[Category: Metal transport]] | [[Category: Metal transport]] | ||
[[Category: Protein-bound iron complex]] | [[Category: Protein-bound iron complex]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||