3ucr: Difference between revisions

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==Crystal structure of the immunoreceptor TIGIT IgV domain==
==Crystal structure of the immunoreceptor TIGIT IgV domain==
<StructureSection load='3ucr' size='340' side='right' caption='[[3ucr]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
<StructureSection load='3ucr' size='340' side='right'caption='[[3ucr]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ucr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UCR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ucr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCR FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.627&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIGIT, VSIG9, VSTM3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ucr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ucr RCSB], [http://www.ebi.ac.uk/pdbsum/3ucr PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ucr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucr OCA], [https://pdbe.org/3ucr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ucr RCSB], [https://www.ebi.ac.uk/pdbsum/3ucr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ucr ProSAT]</span></td></tr>
<table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.,Stengel KF, Harden-Bowles K, Yu X, Rouge L, Yin J, Comps-Agrar L, Wiesmann C, Bazan JF, Eaton DL, Grogan JL Proc Natl Acad Sci U S A. 2012 Mar 15. PMID:22421438<ref>PMID:22421438</ref>
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.,Stengel KF, Harden-Bowles K, Yu X, Rouge L, Yin J, Comps-Agrar L, Wiesmann C, Bazan JF, Eaton DL, Grogan JL Proc Natl Acad Sci U S A. 2012 Mar 15. PMID:22421438<ref>PMID:22421438</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3ucr" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bazan, J F.]]
[[Category: Large Structures]]
[[Category: Rouge, L.]]
[[Category: Bazan JF]]
[[Category: Stengel, K F.]]
[[Category: Rouge L]]
[[Category: Wiesmann, C.]]
[[Category: Stengel KF]]
[[Category: Yin, J P.]]
[[Category: Wiesmann C]]
[[Category: Igsf]]
[[Category: Yin JP]]
[[Category: Immuno receptor]]
[[Category: Membrane protein]]
[[Category: Nectin-2]]
[[Category: Nectin-3]]
[[Category: Pvr]]
[[Category: Pvr/tigit/nectins/ig superfamily/signal transduction]]
[[Category: Signaling protein]]

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