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==Crystal Structure of N5-Carboxyaminoimidazole Ribonucleotide Mutase from Staphylococcus aureus==
==Crystal Structure of N5-Carboxyaminoimidazole Ribonucleotide Mutase from Staphylococcus aureus==
<StructureSection load='3ors' size='340' side='right' caption='[[3ors]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='3ors' size='340' side='right'caption='[[3ors]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ors]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ORS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ORS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ors]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ORS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ORS FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3orq|3orq]], [[3orr|3orr]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NWMN_0933, purE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46170 Staphylococcus aureus subsp. aureus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ors FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ors OCA], [https://pdbe.org/3ors PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ors RCSB], [https://www.ebi.ac.uk/pdbsum/3ors PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ors ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-(carboxyamino)imidazole_ribonucleotide_mutase 5-(carboxyamino)imidazole ribonucleotide mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.18 5.4.99.18] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ors FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ors OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ors RCSB], [http://www.ebi.ac.uk/pdbsum/3ors PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/A0A0H3K7Y1_STAAE A0A0H3K7Y1_STAAE] Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).[HAMAP-Rule:MF_01929][PIRNR:PIRNR001338]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.,Brugarolas P, Duguid EM, Zhang W, Poor CB, He C Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):707-15. Epub 2011 Jul 12. PMID:21795812<ref>PMID:21795812</ref>
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.,Brugarolas P, Duguid EM, Zhang W, Poor CB, He C Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):707-15. Epub 2011 Jul 12. PMID:21795812<ref>PMID:21795812</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3ors" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phosphoribosylaminoimidazole carboxylase 3D structures|Phosphoribosylaminoimidazole carboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Staphylococcus aureus subsp. aureus]]
[[Category: Large Structures]]
[[Category: Brugarolas, P.]]
[[Category: Staphylococcus aureus subsp. aureus str. Newman]]
[[Category: Duguid, E M.]]
[[Category: Brugarolas P]]
[[Category: He, C.]]
[[Category: Duguid EM]]
[[Category: Poor, C B.]]
[[Category: He C]]
[[Category: Zhang, W.]]
[[Category: Poor CB]]
[[Category: Biosynthetic protein]]
[[Category: Zhang W]]
[[Category: Isomerase]]

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