3o9p: Difference between revisions
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==The structure of the Escherichia coli murein tripeptide binding protein MppA== | ==The structure of the Escherichia coli murein tripeptide binding protein MppA== | ||
<StructureSection load='3o9p' size='340' side='right' caption='[[3o9p]], [[Resolution|resolution]] 2.07Å' scene=''> | <StructureSection load='3o9p' size='340' side='right'caption='[[3o9p]], [[Resolution|resolution]] 2.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3o9p]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3o9p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O9P FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o9p OCA], [https://pdbe.org/3o9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o9p RCSB], [https://www.ebi.ac.uk/pdbsum/3o9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o9p ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MPPA_ECOLI MPPA_ECOLI] Essential for the uptake of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha-linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein.,Maqbool A, Levdikov VM, Blagova EV, Herve M, Horler RS, Wilkinson AJ, Thomas GH J Biol Chem. 2011 Sep 9;286(36):31512-21. Epub 2011 Jun 24. PMID:21705338<ref>PMID:21705338</ref> | Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein.,Maqbool A, Levdikov VM, Blagova EV, Herve M, Horler RS, Wilkinson AJ, Thomas GH J Biol Chem. 2011 Sep 9;286(36):31512-21. Epub 2011 Jun 24. PMID:21705338<ref>PMID:21705338</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3o9p" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Blagova EV]] | ||
[[Category: | [[Category: Levdikov VM]] | ||
[[Category: | [[Category: Maqbool A]] | ||
[[Category: Thomas GH]] | |||
[[Category: | [[Category: Wilkinson AJ]] | ||
[[Category: | |||