3o9p: Difference between revisions

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==The structure of the Escherichia coli murein tripeptide binding protein MppA==
==The structure of the Escherichia coli murein tripeptide binding protein MppA==
<StructureSection load='3o9p' size='340' side='right' caption='[[3o9p]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='3o9p' size='340' side='right'caption='[[3o9p]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3o9p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O9P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O9P FirstGlance]. <br>
<table><tr><td colspan='2'>[[3o9p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O9P FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b1329, JW1322, mppA, ynaH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MHI:L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC+ACID'>MHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o9p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o9p RCSB], [http://www.ebi.ac.uk/pdbsum/3o9p PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o9p OCA], [https://pdbe.org/3o9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o9p RCSB], [https://www.ebi.ac.uk/pdbsum/3o9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o9p ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPPA_ECOLI MPPA_ECOLI] Essential for the uptake of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha-linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein.,Maqbool A, Levdikov VM, Blagova EV, Herve M, Horler RS, Wilkinson AJ, Thomas GH J Biol Chem. 2011 Sep 9;286(36):31512-21. Epub 2011 Jun 24. PMID:21705338<ref>PMID:21705338</ref>
Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein.,Maqbool A, Levdikov VM, Blagova EV, Herve M, Horler RS, Wilkinson AJ, Thomas GH J Biol Chem. 2011 Sep 9;286(36):31512-21. Epub 2011 Jun 24. PMID:21705338<ref>PMID:21705338</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3o9p" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Blagova, E V.]]
[[Category: Large Structures]]
[[Category: Levdikov, V M.]]
[[Category: Blagova EV]]
[[Category: Maqbool, A.]]
[[Category: Levdikov VM]]
[[Category: Thomas, G H.]]
[[Category: Maqbool A]]
[[Category: Wilkinson, A J.]]
[[Category: Thomas GH]]
[[Category: Murein tripeptide]]
[[Category: Wilkinson AJ]]
[[Category: Oligopeptide binding protein]]
[[Category: Peptide binding protein-peptide complex]]
[[Category: Periplasmic protein]]

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