1akm: Difference between revisions

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-[[Image:1akm.gif|left|200px]]
- {{Structure
+==ORNITHINE TRANSCARBAMYLASE FROM ESCHERICHIA COLI==
-|PDB= 1akm |SIZE=350|CAPTION= <scene name='initialview01'>1akm</scene>, resolution 2.8&Aring;
+<StructureSection load='1akm' size='340' side='right'caption='[[1akm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[1akm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AKM FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-|GENE= ARGI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1akm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1akm OCA], [https://pdbe.org/1akm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1akm RCSB], [https://www.ebi.ac.uk/pdbsum/1akm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1akm ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OTC1_ECOLI OTC1_ECOLI] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.<ref>PMID:3072022</ref> <ref>PMID:789338</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ak/1akm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1akm ConSurf].
+<div style="clear:both"></div>
-'''ORNITHINE TRANSCARBAMYLASE FROM ESCHERICHIA COLI'''
+==See Also==
+*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-AKM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKM OCA].
+__TOC__
+</StructureSection>
-==Reference==
-Crystal structure at 2.8 A resolution of anabolic ornithine transcarbamylase from Escherichia coli., Jin L, Seaton BA, Head JF, Nat Struct Biol. 1997 Aug;4(8):622-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9253409 9253409]
 [[Category: Escherichia coli]]
-[[Category: Ornithine carbamoyltransferase]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Head JF]]
-[[Category: Head, J F.]]
+[[Category: Jin L]]
-[[Category: Jin, L.]]
+[[Category: Seaton B]]
-[[Category: Seaton, B.]]
-[[Category: anabolic]]
-[[Category: carbamyl phosphate]]
-[[Category: transferase]]
-[[Category: urea cycle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:58:56 2008''