4lm7: Difference between revisions

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OCA

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 ==Crystal structure of HCoV-OC43 N-NTD complexed with UMP==
-<StructureSection load='4lm7' size='340' side='right' caption='[[4lm7]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
+<StructureSection load='4lm7' size='340' side='right'caption='[[4lm7]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4lm7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LM7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LM7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4lm7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_coronavirus_OC43 Human coronavirus OC43]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LM7 FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lm9|4lm9]], [[4lmc|4lmc]], [[4lmt|4lmt]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lm7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lm7 RCSB], [http://www.ebi.ac.uk/pdbsum/4lm7 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lm7 OCA], [https://pdbe.org/4lm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lm7 RCSB], [https://www.ebi.ac.uk/pdbsum/4lm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lm7 ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NCAP_CVHOC NCAP_CVHOC] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.[HAMAP-Rule:MF_04096]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 13: / Line 16: @@
 Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target.,Lin SY, Liu CL, Chang YM, Zhao J, Perlman S, Hou MH J Med Chem. 2014 Mar 27;57(6):2247-57. doi: 10.1021/jm500089r. Epub 2014 Mar 12. PMID:24564608<ref>PMID:24564608</ref>
-From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4lm7" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Hou, M H.]]
+[[Category: Human coronavirus OC43]]
-[[Category: Lin, S Y.]]
+[[Category: Large Structures]]
-[[Category: Liu, C L.]]
+[[Category: Hou MH]]
-[[Category: N-terminal domain]]
+[[Category: Lin SY]]
-[[Category: Nucleocapsid protein]]
+[[Category: Liu CL]]
-[[Category: Rna binding]]
-[[Category: Rna binding protein]]