2ylr: Difference between revisions

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 ==SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: COMPLEX WITH NADP==
-<StructureSection load='2ylr' size='340' side='right' caption='[[2ylr]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
+<StructureSection load='2ylr' size='340' side='right'caption='[[2ylr]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2ylr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLR OCA]. <br>
+<table><tr><td colspan='2'>[[2ylr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YLR FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w4x|1w4x]], [[2ylx|2ylx]], [[2ylz|2ylz]], [[2ylt|2ylt]], [[2ym1|2ym1]], [[2ym2|2ym2]], [[2ylw|2ylw]], [[2yls|2yls]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ylr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ylr OCA], [https://pdbe.org/2ylr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ylr RCSB], [https://www.ebi.ac.uk/pdbsum/2ylr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ylr ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ylr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ylr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ylr RCSB], [http://www.ebi.ac.uk/pdbsum/2ylr PDBsum]</span></td></tr>
+</table>
-<table>
+== Function ==
+[https://www.uniprot.org/uniprot/PAMO_THEFY PAMO_THEFY] Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl acetate. Can also oxidize other aromatic ketones (benzylacetone, alpha-methylphenylacetone and 4-hydroxyacetophenone), some aliphatic ketones (dodecan-2-one and bicyclohept-2-en-6-one) and sulfides (e.g. methyl 4-tolylsulfide).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 Snapshots of Enzymatic Baeyer-Villiger Catalysis: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION.,Orru R, Dudek HM, Martinoli C, Torres Pazmino DE, Royant A, Weik M, Fraaije MW, Mattevi A J Biol Chem. 2011 Aug 19;286(33):29284-91. Epub 2011 Jun 22. PMID:21697090<ref>PMID:21697090</ref>
-From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2ylr" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Phenylacetone monooxygenase]]
+[[Category: Large Structures]]
 [[Category: Thermobifida fusca]]
-[[Category: Dudek, H M.]]
+[[Category: Dudek HM]]
-[[Category: Fraaije, M W.]]
+[[Category: Fraaije MW]]
-[[Category: Martinoli, C.]]
+[[Category: Martinoli C]]
-[[Category: Mattevi, A.]]
+[[Category: Mattevi A]]
-[[Category: Orru, R.]]
+[[Category: Orru R]]
-[[Category: Pazmino, D E.Torres.]]
+[[Category: Royant A]]
-[[Category: Royant, A.]]
+[[Category: Torres Pazmino DE]]
-[[Category: Weik, M.]]
+[[Category: Weik M]]
-[[Category: Baeyer-villiger reaction]]
-[[Category: Fad]]
-[[Category: Oxidoreductase]]
-[[Category: Oxygenase]]