2q0c: Difference between revisions

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 ==Terminal uridylyl transferase 4 from Trypanosoma brucei with bound CTP==
-<StructureSection load='2q0c' size='340' side='right' caption='[[2q0c]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+<StructureSection load='2q0c' size='340' side='right'caption='[[2q0c]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2q0c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q0C OCA]. <br>
+<table><tr><td colspan='2'>[[2q0c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q0C FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ikf|2ikf]], [[2nom|2nom]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TUT4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q0c OCA], [https://pdbe.org/2q0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q0c RCSB], [https://www.ebi.ac.uk/pdbsum/2q0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q0c ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
+</table>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q0c RCSB], [http://www.ebi.ac.uk/pdbsum/2q0c PDBsum]</span></td></tr>
+== Function ==
-<table>
+[https://www.uniprot.org/uniprot/TUT4_TRYB2 TUT4_TRYB2] Terminal uridylyltransferase which, specifically, catalyzes the addition of Us to the 3'-hydroxyl group of single-stranded RNAs with a 3'-terminal U.<ref>PMID:17189640</ref> <ref>PMID:17785418</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q0/2q0c_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q0/2q0c_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q0c ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
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 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases.,Stagno J, Aphasizheva I, Aphasizhev R, Luecke H Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14634-9. Epub 2007 Sep 4. PMID:17785418<ref>PMID:17785418</ref>
-From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2q0c" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[RNA uridylyltransferase|RNA uridylyltransferase]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: RNA uridylyltransferase]]
+[[Category: Large Structures]]
-[[Category: Luecke, H.]]
+[[Category: Trypanosoma brucei]]
-[[Category: Stagno, J.]]
+[[Category: Luecke H]]
-[[Category: Nucleotidyltransferase]]
+[[Category: Stagno J]]
-[[Category: Rna-editing]]
-[[Category: Transferase]]
-[[Category: Trypanosoma]]
-[[Category: Tutase]]
-[[Category: Utp-binding]]