2eg9: Difference between revisions
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== | ==Crystal structure of the truncated extracellular domain of mouse CD38== | ||
<StructureSection load='2eg9' size='340' side='right'caption='[[2eg9]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2eg9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EG9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eg9 OCA], [https://pdbe.org/2eg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eg9 RCSB], [https://www.ebi.ac.uk/pdbsum/2eg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eg9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eg9 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CD38_MOUSE CD38_MOUSE] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2eg9_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eg9 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Hara-Yokoyama M]] | |||
[[Category: Kukimoto-Niino M]] | |||
[[Category: Hara-Yokoyama | [[Category: Mishima C]] | ||
[[Category: Kukimoto-Niino | [[Category: Shirouzu M]] | ||
[[Category: Mishima | [[Category: Terada T]] | ||
[[Category: Wakiyama M]] | |||
[[Category: Shirouzu | [[Category: Yokoyama S]] | ||
[[Category: Terada | |||
[[Category: Wakiyama | |||
[[Category: Yokoyama | |||
Latest revision as of 08:11, 17 October 2024
Crystal structure of the truncated extracellular domain of mouse CD38Crystal structure of the truncated extracellular domain of mouse CD38
Structural highlights
FunctionCD38_MOUSE Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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