Nucleosomes: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Eran Hodis, Joel L. Sussman, Harry Greenblatt, Jaime Prilusky, Angel Herraez, David Canner, Michal Harel, Karl Oberholser, Alexander Berchansky

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-This page offers some large scenes of a nucleosome ([[1aoi]]) suitable for projection in biochemistry classes. For a general introduction, see Wikipedia: [http://en.wikipedia.org/wiki/Nucleosomes Nucleosome]. For a list of nucleosome PDB entries, see Category: Nucleosome ''(technical problem getting this link to work)'' [[Category:Nucleosome | Category: Nucleosome]].
+For a general introduction beyond what is provided below, please see Wikipedia: [http://en.wikipedia.org/wiki/Nucleosomes Nucleosome]. For a list of nucleosome structures, see [[:Category:Nucleosome | Category: Nucleosome]].
-==Scenes for Projection in Biochem Classes==
+==Scenes for Projection in Biochemistry Classes==
-<applet load="1aoi" size="600" color="white" frame="true" align="right" spinBox="true"
-caption="1aoi, resolution 2.80&Aring;" />
+This section offers some large scenes of a nucleosome ([[1aoi]]), as determined in [http://www.mol.biol.ethz.ch/groups/richmond  Tim Richmond's lab], suitable for projection in biochemistry classes.
+<applet load="1aoi" size="450" color="white" frame="true" align="right" caption="[[1aoi]], resolution 2.80&Aring;" script="Nucleosomes/Rockets/1" />
 <big>
-. '''<scene name='1aoi/Composition/1'>Composition</scene>: <font color='#808080'>DNA</font>, <font color='#7e6c54'>Protein</font>.'''
+. '''<scene name='Nucleosomes/Composition/2'>Composition</scene>: <font color='#808080'>DNA</font>, <font color='#7e6c54'>Protein</font>.'''
-. '''<scene name='Nucleosomes/Dna/1'>DNA</scene>'''
+. '''<scene name='Nucleosomes/Dna/3'>DNA</scene>'''
+<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>display displayed,*:i,*:j</scriptWhenChecked>
+    <scriptWhenUnchecked>hide hidden,*:i,*:j</scriptWhenUnchecked>
+    <checked>true</checked>
+    <text></text>
+  </jmolCheckbox>
+</jmol>
-<big>Histone color key: '''<font color='red'>H2a</font> <font color='orange'>H2b</font> <font color='green'>H3</font> <font color='blue'>H4</font>'''</big>
+. '''<scene name='Nucleosomes/Histones/6'>Histones</scene>'''
+<br>
+&nbsp;&nbsp;
+<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>display displayed,*:c,*:g</scriptWhenChecked>
+    <scriptWhenUnchecked>hide hidden,*:c,*:g</scriptWhenUnchecked>
+    <checked>true</checked>
+    <text></text>
+  </jmolCheckbox>
+</jmol><big>'''<font color='red'>H2a</font>'''</big>
+&nbsp;
+<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>display displayed,*:d,*:h</scriptWhenChecked>
+    <scriptWhenUnchecked>hide hidden,*:d,*:h</scriptWhenUnchecked>
+    <checked>true</checked>
+    <text></text>
+  </jmolCheckbox>
+</jmol><big>'''<font color='orange'>H2b</font>'''</big>
+&nbsp;
+<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>display displayed,*:a,*:e</scriptWhenChecked>
+    <scriptWhenUnchecked>hide hidden,*:a,*:e</scriptWhenUnchecked>
+    <checked>true</checked>
+    <text></text>
+  </jmolCheckbox>
+</jmol><big>'''<font color='green'>H3</font>'''</big>
+&nbsp;
+<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>display displayed,*:b,*:f</scriptWhenChecked>
+    <scriptWhenUnchecked>hide hidden,*:b,*:f</scriptWhenUnchecked>
+    <checked>true</checked>
+    <text></text>
+  </jmolCheckbox>
+</jmol><big>'''<font color='blue'>H4</font>'''</big>
-. '''<scene name='Nucleosomes/Histones/1'>Histones</scene>'''
-. '''<scene name='1aoi/Rockets/1'>Secondary Structure</scene>'''
+. '''<scene name='Nucleosomes/Rockets/4'>Secondary Structure</scene>'''
+<ul>
+<li><scene name='Nucleosomes/Rockets/10'>H2a and H2b only</scene></li>
+<li><scene name='Nucleosomes/Rockets/11'>H3 and H4 only</scene></li>
+</ul>
 </big>
+<scene name='1aoi/Introduction/2'>The nucleosome core particle</scene> contains two copies of each histone <font color=tan>'''protein'''</font> (<font color=tan>'''H2A, H2B, H3, H4'''</font>) and 146 basepairs (bp) of superhelical <font color=purple>'''DNA'''</font> wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).<br />
+Examples of [[Archaeal_Histones]]
+<br clear='right'>
+==3D structures of histone==
-<jmol>
+[[Histone]]
-  <jmolCheckbox>
-    <scriptWhenChecked>script to execute when the checkbox is checked</scriptWhenChecked>
+==Additional Resources==
-    <scriptWhenUnchecked>script to execute when the checkbox is unchecked</scriptWhenUnchecked>
+For Additional Information, See: [[Nucleic Acids]]
-    <text>text of the checkbox</text>
-  </jmolCheckbox>
+== Files for 3D printer ==
-</jmol>
+<i class="fas fa-cubes"></i> Nucleosome by [[User:Marius Mihasan|Marius Mihasan]] [https://3dprint.nih.gov/discover/3DPX-015090  <i class="fas fa-download"></i>]
+[[Category:Nucleosome]]
+[[Category:3D printer files]]