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== | ==Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution== | ||
[[http://www.uniprot.org/uniprot/FOSB_STAAN FOSB_STAAN | <StructureSection load='4naz' size='340' side='right'caption='[[4naz]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4naz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4naz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4naz OCA], [https://pdbe.org/4naz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4naz RCSB], [https://www.ebi.ac.uk/pdbsum/4naz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4naz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FOSB_STAAN FOSB_STAAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity). | |||
== | ==See Also== | ||
[[ | *[[Metallothiol transferase FosB|Metallothiol transferase FosB]] | ||
__TOC__ | |||
</StructureSection> | |||
< | [[Category: Large Structures]] | ||
[[Category: | [[Category: Staphylococcus aureus subsp. aureus N315]] | ||
[[Category: Armstrong | [[Category: Armstrong RN]] | ||
[[Category: Cook | [[Category: Cook PD]] | ||
[[Category: Goodman | [[Category: Goodman MC]] | ||
[[Category: Harp | [[Category: Harp J]] | ||
[[Category: Jagessar | [[Category: Jagessar K]] | ||
[[Category: Keithly | [[Category: Keithly ME]] | ||
[[Category: Thompson | [[Category: Thompson MK]] | ||
Latest revision as of 15:32, 1 March 2024
Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom ResolutionCrystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution
Structural highlights
FunctionFOSB_STAAN Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity). See Also |
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