2mls: Difference between revisions
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New page: '''Unreleased structure''' The entry 2mls is ON HOLD Authors: Koppisetti, R.K., Fulcher, Y.G., Prior, S.H., Lenoir, M., Overduin, M., Van Doren, S.R. Description: Membrane Bilayer comp... |
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==Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Beta-face== | |||
<StructureSection load='2mls' size='340' side='right'caption='[[2mls]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2mls]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mls OCA], [https://pdbe.org/2mls PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mls RCSB], [https://www.ebi.ac.uk/pdbsum/2mls PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mls ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MMP12_HUMAN MMP12_HUMAN] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. | |||
==See Also== | |||
*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fulcher YG]] | |||
[[Category: Koppisetti RK]] | |||
[[Category: Lenoir M]] | |||
[[Category: Overduin M]] | |||
[[Category: Prior SH]] | |||
[[Category: Van Doren SR]] | |||
Latest revision as of 10:01, 1 May 2024
Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Beta-faceMembrane Bilayer complex with Matrix Metalloproteinase-12 at its Beta-face
Structural highlights
FunctionMMP12_HUMAN May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. See Also |
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