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{{STRUCTURE_4ol9|  PDB=4ol9  |  SCENE=  }}
===Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate===


==Function==
==Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate==
[[http://www.uniprot.org/uniprot/PANE_MYCTU PANE_MYCTU]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).  
<StructureSection load='4ol9' size='340' side='right'caption='[[4ol9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4ol9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OL9 FirstGlance]. <br>
[[4ol9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OL9 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
[[Category: 2-dehydropantoate 2-reductase]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=OXM:OXAMIC+ACID'>OXM</scene></td></tr>
[[Category: Disease, Seattle Structural Genomics Center for Infectious.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ol9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ol9 OCA], [https://pdbe.org/4ol9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ol9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ol9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ol9 ProSAT]</span></td></tr>
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
</table>
[[Category: Ketopantoate reductase]]
== Function ==
[[Category: National institute of allergy and infectious disease]]
[https://www.uniprot.org/uniprot/PANE_MYCTU PANE_MYCTU] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).
[[Category: Niaid]]
__TOC__
[[Category: Oxidoreductase]]
</StructureSection>
[[Category: Seattle structural genomics center for infectious disease]]
[[Category: Large Structures]]
[[Category: Ssgcid]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

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