4ntk: Difference between revisions

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'''Unreleased structure'''


The entry 4ntk is ON HOLD  until Paper Publication
==QueD from E. coli==
 
<StructureSection load='4ntk' size='340' side='right'caption='[[4ntk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors: Bandarian, V., Roberts, S.A., Miles, Z.D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ntk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NTK FirstGlance]. <br>
Description: QueD from E. coli
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ZSP:2-AMINO-6-[(1Z)-1,2-DIHYDROXYPROP-1-EN-1-YL]-7,8-DIHYDROPTERIDIN-4(3H)-ONE'>ZSP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntk OCA], [https://pdbe.org/4ntk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ntk RCSB], [https://www.ebi.ac.uk/pdbsum/4ntk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/QUED_ECOLI QUED_ECOLI] Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP.
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Bandarian V]]
[[Category: Miles ZD]]
[[Category: Roberts SA]]

Latest revision as of 15:35, 1 March 2024

QueD from E. coliQueD from E. coli

Structural highlights

4ntk is a 6 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

QUED_ECOLI Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP.

4ntk, resolution 1.60Å

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