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== | ==Crystal structure of the catalytic subunit of human primase bound to UTP and Mn== | ||
[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN | <StructureSection load='4lil' size='340' side='right'caption='[[4lil]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4lil]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lil OCA], [https://pdbe.org/4lil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lil RCSB], [https://www.ebi.ac.uk/pdbsum/4lil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lil ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. | |||
== | ==See Also== | ||
[[ | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
< | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chazin WJ]] | ||
[[Category: | [[Category: Eichman BF]] | ||
[[Category: | [[Category: Vaithiyalingam S]] | ||
[[Category: | |||
Latest revision as of 15:19, 1 March 2024
Crystal structure of the catalytic subunit of human primase bound to UTP and MnCrystal structure of the catalytic subunit of human primase bound to UTP and Mn
Structural highlights
FunctionPRI1_HUMAN DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. See Also |
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