4l4z: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{STRUCTURE_4l4z|  PDB=4l4z  |  SCENE=  }}
-===Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition===
-{{ABSTRACT_PUBMED_24047255}}
-==Function==
+==Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition==
-[[http://www.uniprot.org/uniprot/LSRR_ECOLI LSRR_ECOLI]] Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes.<ref>PMID:15601708</ref> <ref>PMID:15743955</ref> <ref>PMID:17557827</ref>
+<StructureSection load='4l4z' size='340' side='right'caption='[[4l4z]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4l4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L4Z FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D5X:(2S)-2,3,3-TRIHYDROXY-4-OXOPENTYL+DIHYDROGEN+PHOSPHATE'>D5X</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l4z OCA], [https://pdbe.org/4l4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l4z RCSB], [https://www.ebi.ac.uk/pdbsum/4l4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l4z ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LSRR_ECOLI LSRR_ECOLI] Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes.<ref>PMID:15601708</ref> <ref>PMID:15743955</ref> <ref>PMID:17557827</ref>
-==About this Structure==
+==See Also==
-[[4l4z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4Z OCA].
+*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:024047255</ref><references group="xtra"/><references/>
+__TOC__
-[[Category: Escherichia coli k-12]]
+</StructureSection>
-[[Category: Eo, Y.]]
+[[Category: Escherichia coli K-12]]
-[[Category: Ha, J H.]]
+[[Category: Large Structures]]
-[[Category: Ryu, K S.]]
+[[Category: Eo Y]]
-[[Category: Dna binding]]
+[[Category: Ha JH]]
-[[Category: Dna transcriptional regulator]]
+[[Category: Ryu KS]]
-[[Category: Phospho-ai-2 binding]]
-[[Category: Removed helix-turn-helix domain]]
-[[Category: Sorc/deor family]]
-[[Category: Transcription regulator]]