4nah: Difference between revisions

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'''Unreleased structure'''


The entry 4nah is ON HOLD
==Inhibitors of 4-Phosphopanthetheine Adenylyltransferase (PPAT)==
 
<StructureSection load='4nah' size='340' side='right'caption='[[4nah]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
Authors: Lahiri, SD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4nah]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAH FirstGlance]. <br>
Description: Inhibitors of 4 -Phosphopanthetheine Adenylyltransferase (PPAT)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2VJ:2-[(2-{(1S,2S)-2-[(3,4-DICHLOROBENZYL)CARBAMOYL]CYCLOHEXYL}-6-ETHYLPYRIMIDIN-4-YL)SULFANYL]-1H-IMIDAZOLE-5-CARBOXYLIC+ACID'>2VJ</scene>, <scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nah OCA], [https://pdbe.org/4nah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nah RCSB], [https://www.ebi.ac.uk/pdbsum/4nah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nah ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAD_STAAW COAD_STAAW] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus MW2]]
[[Category: Lahiri SD]]

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