4je3: Difference between revisions

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-{{STRUCTURE_4je3|  PDB=4je3  |  SCENE=  }}
-===An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation===
-{{ABSTRACT_PUBMED_24075991}}
-==Function==
+==An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation==
-[[http://www.uniprot.org/uniprot/IML3_YEAST IML3_YEAST]] Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation.<ref>PMID:11361335</ref> <ref>PMID:15241623</ref>  [[http://www.uniprot.org/uniprot/CHL4_YEAST CHL4_YEAST]] Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle-microtubule attachments and proper chromosome segregation.<ref>PMID:9339342</ref>
+<StructureSection load='4je3' size='340' side='right'caption='[[4je3]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[4je3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JE3 FirstGlance]. <br>
-[[4je3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JE3 OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.282&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4je3 OCA], [https://pdbe.org/4je3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4je3 RCSB], [https://www.ebi.ac.uk/pdbsum/4je3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4je3 ProSAT]</span></td></tr>
-==Reference==
+</table>
-<ref group="xtra">PMID:024075991</ref><references group="xtra"/><references/>
+== Function ==
+[https://www.uniprot.org/uniprot/CENPL_YEAST CENPL_YEAST] Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.<ref>PMID:11361335</ref> <ref>PMID:15241623</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Harrison, S C.]]
+[[Category: Harrison SC]]
-[[Category: Hinshaw, S M.]]
+[[Category: Hinshaw SM]]
-[[Category: Beta sheet]]
-[[Category: Cell cycle]]
-[[Category: Chromosome segregation]]
-[[Category: Iml3-chl4 dimer]]
-[[Category: Kinetochore]]
-[[Category: Nucleus]]