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==Crystal structure of human primase catalytic subunit== | |||
<StructureSection load='4mhq' size='340' side='right'caption='[[4mhq]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4mhq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MHQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhq OCA], [https://pdbe.org/4mhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mhq RCSB], [https://www.ebi.ac.uk/pdbsum/4mhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. | |||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: An JY]] | |||
[[Category: Eom SH]] | |||
[[Category: Kang JY]] | |||
[[Category: Kim TG]] | |||
[[Category: Lee JG]] | |||
[[Category: Lee Y]] | |||
[[Category: Lim JJ]] | |||
[[Category: Park KR]] | |||
[[Category: Wang J]] | |||
[[Category: Youn HS]] | |||
Latest revision as of 11:56, 20 March 2024
Crystal structure of human primase catalytic subunitCrystal structure of human primase catalytic subunit
Structural highlights
FunctionPRI1_HUMAN DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. See Also |
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