4max: Difference between revisions

No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_4max|  PDB=4max  |  SCENE=  }}
===Crystal structure of Synechococcus sp. PCC 7002 globin at cryogenic temperature with heme modification===
{{ABSTRACT_PUBMED_23999883}}


==About this Structure==
==Crystal structure of Synechococcus sp. PCC 7002 globin at cryogenic temperature with heme modification==
[[4max]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_itombwensis Xenopus itombwensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4i0v 4i0v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAX OCA].  
<StructureSection load='4max' size='340' side='right'caption='[[4max]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4max]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_sp._PCC_7002 Synechococcus sp. PCC 7002]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4i0v 4i0v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MAX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.444&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEB:HEME+B/C'>HEB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4max FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4max OCA], [https://pdbe.org/4max PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4max RCSB], [https://www.ebi.ac.uk/pdbsum/4max PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4max ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8RT58_SYNP2 Q8RT58_SYNP2]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The X-ray structures of the hemoglobin from Synechococcus sp. PCC 7002 (GlbN) were solved in the ferric bis-histidine (1.44 A resolution) and cyanide-bound (2.25 A resolution) states with covalently attached heme. The two structures illustrate the conformational changes and cavity opening caused by exogenous ligand binding. They also reveal an unusually distorted heme, ruffled as in c cytochromes. Comparison to the solution structure demonstrates the influence of crystal packing on several structural elements, whereas comparison to GlbN from Synechocystis sp. PCC 6803 shows subtle differences in heme geometries and environment. The new structures will be instrumental in elucidating GlbN reactivity. (c) Proteins 2013;. (c) 2013 Wiley Periodicals, Inc.


==Reference==
The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X-ray and NMR structures.,Wenke BB, Lecomte JT, Heroux A, Schlessman JL Proteins. 2013 Sep 2. doi: 10.1002/prot.24409. PMID:23999883<ref>PMID:23999883</ref>
<ref group="xtra">PMID:023999883</ref><references group="xtra"/><references/>
 
[[Category: Xenopus itombwensis]]
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Heroux, A.]]
</div>
[[Category: Lecomte, J T.J.]]
<div class="pdbe-citations 4max" style="background-color:#fffaf0;"></div>
[[Category: Schlessman, J L.]]
== References ==
[[Category: Wenke, B B.]]
<references/>
[[Category: 2/2 globin]]
__TOC__
[[Category: 2/2 hemoglobin]]
</StructureSection>
[[Category: Glbn]]
[[Category: Large Structures]]
[[Category: Hemeprotein]]
[[Category: Synechococcus sp. PCC 7002]]
[[Category: Ros/rns detoxification]]
[[Category: Heroux A]]
[[Category: Trhbn]]
[[Category: Lecomte JTJ]]
[[Category: Unknown function]]
[[Category: Schlessman JL]]
[[Category: Wenke BB]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA